Table 3.
Measure | Baseline | Short-term Follow-up^ |
Long-term Follow-up+ |
p |
---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | ||
H & Y Staging (I–V) | ||||
“On” | 2.5 (2–4) | 2.0 (0–4) | 2.5 (0–4 | .002* |
“Off” | 4.00 (3–5) | 3.0 (2–5) | 3.0 (2–5) | .001* |
UPDRS Total (0–199) | ||||
“On” | 49.2 (9.2) | 27.4 (12.4) | 43.1 (22.6) | .001* |
“Off” | 93.9 (13.6) | 58.8 (14.8) | 70.9 (18.0) | .001* |
UPDRS Motor (0–144) | ||||
“On” | 32.2 (7.1) | 17.9 (9.4) | 27.3 (14.8) | .001* |
“Off” | 58.3 (10.4) | 37.2 (10.3) | 44.3 (12.4) | .001* |
UPDRS ADL (0–51) | ||||
“On” | 15.6 (4.5) | 9.1 (3.2) | 14.3 (7.3) | .001* |
“Off” | 31.6 (3.7) | 19.2 (4.7) | 23.8 (6.8) | .001* |
UPDRS Dyskinesias | ||||
Duration (Median) | 2.0 (Range 1–3) | 1.0 (Range 0–2) | 1.0 (Range 0–4) | .001* |
Disability (Median) | 2.0 (Range 1–3) | 0.5 (Range 0–2) | 0.5 (Range 0–4) | .001* |
ADL=activities of daily living; H&Y=Hoehn and Yahr Staging, higher number indicates more impairment; UPDRS=United Parkinson’s disease Rating Scale, higher number indicates more impairment.
p<.01;
Mean = 5.3 months; SD = 2.7 months;
Mean = 5.1 years, SD = 1.9 years