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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Surg Neurol. 2008 Jun 2;71(5):551–558. doi: 10.1016/j.surneu.2008.03.039

Table 3.

Neurological Outcome on Short and Long-Term Follow-up for Unilateral Pallidotomy Patients (n=18)

Measure Baseline Short-term
Follow-up^
Long-term
Follow-up+
p
Mean (SD) Mean (SD) Mean (SD)

H & Y Staging (I–V)
  “On” 2.5 (2–4) 2.0 (0–4) 2.5 (0–4 .002*
  “Off” 4.00 (3–5) 3.0 (2–5) 3.0 (2–5) .001*

UPDRS Total (0–199)
  “On” 49.2 (9.2) 27.4 (12.4) 43.1 (22.6) .001*
  “Off” 93.9 (13.6) 58.8 (14.8) 70.9 (18.0) .001*

UPDRS Motor (0–144)
  “On” 32.2 (7.1) 17.9 (9.4) 27.3 (14.8) .001*
  “Off” 58.3 (10.4) 37.2 (10.3) 44.3 (12.4) .001*

UPDRS ADL (0–51)
  “On” 15.6 (4.5) 9.1 (3.2) 14.3 (7.3) .001*
  “Off” 31.6 (3.7) 19.2 (4.7) 23.8 (6.8) .001*

UPDRS Dyskinesias
  Duration (Median) 2.0 (Range 1–3) 1.0 (Range 0–2) 1.0 (Range 0–4) .001*
  Disability (Median) 2.0 (Range 1–3) 0.5 (Range 0–2) 0.5 (Range 0–4) .001*

ADL=activities of daily living; H&Y=Hoehn and Yahr Staging, higher number indicates more impairment; UPDRS=United Parkinson’s disease Rating Scale, higher number indicates more impairment.

*

p<.01;

^

Mean = 5.3 months; SD = 2.7 months;

+

Mean = 5.1 years, SD = 1.9 years