Table 4.
Short and Long-Term Neuropsychological Outcome for Unilateral Pallidotomy Patients (n=18)
| Measure | Baseline Mean (SD) |
Short-Term Follow-up^ Mean (SD) |
Long-Term Follow-up+ Mean (SD) |
p |
|---|---|---|---|---|
| Mental Status | ||||
| MMSE (0–30) | 27.4 (3.5) | 27.3 (3.1) | 24.7 (5.4) | .01↓ |
| Verbal Learning | ||||
| CVLT Total 1–5(0–80) | 37.4 (8.4) | 35.1 (11.9) | 35.8 (14.9) | .59 |
| CVLT Long Delay (0–16) | 7.50 (2.7) | 7.6 (3.9) | 6.80 (4.8) | .63 |
| CVLT Discriminability | 89.0 (7.9) | 84.3 (22.0) | 83.6 (13.8) | .03↓ |
| Language | ||||
| BNT (0–60) | 51.6 (9.3) | 52.8 (7.4) | 53.4 (6.6) | .68 |
| COWAT-FAS | 29.1 (12.6) | 27.8 (14.1) | 26.6 (17.2) | .47 |
| Visuospatial | ||||
| Hooper (0–30) | 22.8 (5.6) | 23.7 (4.9) | 21.7 (7.7) | .16 |
| Info. Processing | ||||
| SDMT | 37.6 (14.7) | 36.8 (16.2) | 30.8 (19.3) | .01↓ |
| Trails A | 53.3 (30.9) | 52.3 (32.4) | 86.2 (70.8) | .04↓ |
| Stroop Word* | 74.9 (24.2) | 76.2 (23.8) | 61.4 (30.8) | .009↓ |
| Stroop Color* | 54.1 (14.9) | 54.4 (15.0) | 41.0 (21.1) | .008↓ |
| Executive Functions | ||||
| Stroop Color Word | 28.7 (11.6) | 28.8 (10.2) | 22.4 (16.6) | .18 |
| Trails B | 181.2 (168) | 162.5 (107) | 188.5 (106) | .18 |
| WCST Total Errors | 56.7 (19.4) | 52.8 (26.0) | 48.0 (28.0) | .69 |
| WCST Persev Errors | 30.9 (17.5) | 28.3 (18.0) | 34.1 (24.2) | .69 |
| Affective Functioning | ||||
| BDI (0–63) | 9.8 (7.2) | 7.7 (6.0) | 10.5 (6.5) | .21 |
Bold=Significant contrasts with significant Time main effect (p<.05);
↓
=Decline.
^
Mean = 5.3 months, SD = 2.7 months;
+
Mean = 5.1 years, SD = 1.9 years
*
Stroop Word and Stroop Color Word=number of items read within a 45 second time interval; CVLT=California Verbal Learning Test, Trials 1–5, Long Delay; Stroop=Stroop Color Word Test, Interference; WCST=Wisconsin Card Sorting Test, Total Errors.