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. Author manuscript; available in PMC: 2009 Nov 19.
Published in final edited form as: J Am Chem Soc. 2008 Oct 28;130(46):15405–15419. doi: 10.1021/ja803575y

Table 1.

Examples of proteins that bind Na+ and K+ ions in states of over-coordination (higher than the coordination in water).

Ion Biomolecule PDB ID # Ligands rave (Å)
Na+ Neurotransmitter Transporter 2A65a 5 2.3
Dialkylglycine decarboxylase 2DKBb 6 2.4
Lysozyme 1V7Tc 6 2.4
Neurotransmitter Transporter 2A65a 6 2.4
Thrombokinase 1BOKd 6 2.5
K+ Chaperon Hsc70 1HPMe 7 3.0
Pyruvate Kinase 1A49f 7 2.8
Chaperon Hsc70 1HPMe 8 2.9
Potassium Channel 1K4Cg 8 2.8
Nonactin n.a.h 8 2.8
a

Reference 13

b

Reference 14

c

Reference 15

d

Reference 16

e

Reference 18

f

Reference 17

g

Reference 20

h

Reference 19