Table 2.

Change in Visual Acuity, Optical Coherence Tomography (OCT), Fluorescein Angiography (FA) and Stereoscopic Color Fundus Photograph Characteristics from Baseline to 12 Months After Focal/Grid Photocoagulation - median (25^th, 75^th percentiles) or N (%)

	Eyes with Non-Center Involved CSME N = 22^a
Visual acuity letter score	−1 (−5, +2)

≥ 15 letters improvement	0
10-14 letters improvement	1 (5%)
5 - 9 letters improvement	3 (14%)
within ± 4 letters	11 (50%)
5 - 9 letters worse	4 (18%)
10-14 letters worse	1 (5%)
≥ 15 letters worse	2 (9%)
OCT characteristics
Central subfield (microns)	−10 (−16, +13)
Total macular volume^b (mm³)	−0.2 (−0.5, +0.1)
Mean inner zone/center unweighted thickness^c (microns)	−8 (−20, +13)
Inner zone volume^d (mm³)	−0.1 (−0.1, +0.1)
Mean unweighted thickness within the grid^e (microns)	−4 (−18, +8)
Max inner subfield thickness^f (microns)	−12 (−27, +11)
Excluding the Central Subfield:
Mean inner zone subfields thickness^g (microns)	−9 (−23, +15)
Mean outer zone subfields thickness^h (microns)	−4 (−15, +19)
Fluorescein angiography characteristics - Disc Areas
Fluorescein leakage within the gridⁱ	−0.70 (−2.06, +0.16)
Cystoid abnormality within the grid^j	0 (0, 0)
Capillary loss within the grid^k	0 (0, +0.01)
Fundus photograph characteristics
DME area within the grid - disc areas	+0.21 (−0.47, +5.05)
ETDRS severity scale
≥ 2 levels better	0
Within 1 level	15 (68%)
≥ 2 levels worse	7 (32%)

Excludes 2 subjects who did not complete 12 month visit

Missing for 6 eyes

Mean thickness of central subfield and 4 inner subfields, Equal weight to all 5 zones. Missing for 2 eyes

Missing for 5 eyes

Mean thickness of central subfield, 4 inner subfields, and 4 outer subfields. Equal weight to all 9 zones. Missing for 2 eyes

Maximum of central subfields and 4 inner subfields

Mean thickness of 4 inner subfields (excluding the center), Missing for 2 eyes

Mean thickness of 4 outer subfields (excluding the inner and center), Missing for 2 eyes

ⁱ

Missing for 4 eyes

Missing for 8 eyes