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. 2009 Aug 17;119(9):2725–2736. doi: 10.1172/JCI39542

Figure 8. Expression of PrP is associated with poorer prognosis.

Figure 8

The 37 patients had surgery done from 2001 to 2003. Patients (n = 16) whose tumors expressed PrP (PrP+) had a median survival time of 360 days. On the other hand, of the 21 patients whose tumors lacked PrP (PrP–), 6 of these patients are still alive as of October of 2008. Four of these patients have already passed 5 years after surgery; 2 others will have passed 5 years in late November of 2008 (2 of the spikes). The other 2 spikes indicate a patient who died 41 months after surgery and a patient who died 52 months after surgery, respectively. This cohort of patients has mean survival time of more than 1,200 days (P < 0.001).