Figure 2.

Frequency histograms of structural and compositional features of the 45 RGG sequences surveyed (Table S1). A) Position of the RGG box region in the proteins. N-terminal (within the first 35% of the protein sequence), C-terminal (last 35% of the protein), Middle, region between. B) Length of the RGG box. C) Spacing between RGG repeats where X may be any residue including Arg and Gly. D) Amino acid composition in terms of type: basic (R, K, H); acidic (D, E); Gly: aromatic (F, Y, W); non-polar amino acids (A, V, L, I, M, P) and polar (S, T, N, Q, C).