Table 5.
Expected mean squared errors for option 2 of the combined model with one array per batch.Table shows the expected mean squared errors associated with a combined model. This layout corresponds to a 2 × 2 × 5 factorial arrangement of sex, time, AZT and their interactions with the 60 pooled muscle samples (2 samples per pool) processed in 60 batches (blocks); each batch has 1 pool.
| Source | DF | Expected mean square (approx.) |
|---|---|---|
| Mean: Housekeeping genes | 1 | σ2 + σ2b + σ2m + Q(Slope) |
| Sex | 1 | σ2 + σ2b + σ2m + Q(Sex) |
| Time | 1 | σ2 + σ2b + σ2m + Q(Time) |
| Sex * Time | 1 | σ2 + σ2b + σ2m + Q(Sex * Time) |
| AZT | 4 | σ2 + σ2b + σ2m + Q(AZT) |
| AZT * Sex | 4 | σ2 + σ2b + σ2m + Q(AZT * Sex) |
| AZT * Time | 4 | σ2 + σ2b + σ2m + Q(AZT * Time) |
| AZT * Sex * Time | 4 | σ2 + σ2b + σ2m + Q(AZT * Sex * Time) |
| Mice within treatment | 39 | σ2 + σ2b + σ2m |