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. 2008 Mar 12;2:133–144. doi: 10.4137/bbi.s550

Table 2.

Property groups of amino acids used to derive features.

Groups Subgroups AAs Groups Subgroups AAs
R groups Nonpolar aliphatic AVLIMG Hydrophobicity groups Hydrophobic VLIMAFPWYCG
Polar uncharged SPTCNQ Hydrophilic basic KHR
Positively charged KHR Hydrophilic acidic DE
Negative DE Hydrophilic polar with uncharged side chain STNQ
Aromatic FYW
Exchange groups E1 KHR Electronic groups Electron donor DEPA
E2 DENQ Weak electron donor VLI
E3 C Electron acceptor KNR
E4 AGPST Weak electron acceptor FYMTQ
E5 ILMV Neutral GHWS
E6 FYW Special AA C
Other groups Charged DEKHRVLI Other groups Tiny AG
Polar DEKHRNTQSYW Bulky FHWYR
Aromatic FHWY Polar-uncharged NQ
Small AGST