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GnRH-neuron-specific deletion of p85α does not disrupt estrous cyclicity. A, Representative estrous cycles as measured by vaginal cytology in WT (top panel), and GnRH-p85αKO (bottom panel) females. C, Cornified; N, nucleated; L, leukocytic. B, Percent of time per stage of estrous cycle. The only abnormality noted in GnRH-p85αKO females was a slight decrease in days spent in proestrus (nucleated vaginal cytology, *, P = 0.002) compared with WT females.
