Figure 2.

Food intake and body weight measurements at the beginning and during 48 h of treatment in experiments 1–3. Con, Virgin control; Lac, lactation + eight pups; Lac + Ins/Lep, lactation + insulin and leptin replacement; −Pups, 48 h pup removal. The lactating rats had significantly greater food intake and body weight compared with controls in all three experiments. *, Significant difference in food intake within the − Pups group during the 48 h (P < 0.05). There were no significant differences in food intake or body weight within any other groups after treatment.