Figure 1. Schematic representation of the Vβ^ω and Vβ^2-4-14 alleles.

(A) Schematic diagrams of the entire TCRβ loci on the Vβ^ω and Vβ^2-4-14 alleles. The loxP sites inserted in place of the DJβ2 clusters and during gene-targeting simplification of the Vβ cluster are indicated by triangles. The relative size of the Vβ cluster and the Dβ-Jβ-Cβ regions are not drawn to scale. (B) Schematic diagrams of the EcoRI restriction fragment length polymorphisms created on the Vβ^ω and Vβ^2-4-14 alleles. Black bars indicate the locations of the Vβ4 and 3'Vβ18 probes.