Table 4.
Genetic Polymorphisms and occurrence of cardiac adverse events
| Freedom from [%] at | |||||||
| Factor | Definition | n | Outcome | 5 years | 10 years | 15 years | P |
| eNos | bb | 141 | Reintervention | 93.9 | 88.7 | 75.9 | 0.041 |
| 4ab | aa/ab | 51 | 87.5 | 67.9 | 62.7 | ||
| bb | 141 | Combined | 89.3 | 56.0 | 13.2 | 0.042 | |
| aa/ab | 51 | 80.4 | 40.6 | 5.1 | |||
| ApoE | 2 3/3 3/3 4 | 182 | Reintervention | 92.3 | 84.5 | 75.1 | 0.001 |
| 2 4/4 4 | 10 | 90.0 | 64.3 | 32.1 | |||
| LIPC | WW/WM | 144 | Reoperation | 96.4 | 74.6 | 27.5 | 0.049 |
| MM | 48 | 89.5 | 54.5 | 9.9 | |||
See Additional File 1for abbreviations of polymorphisms. M: Mutation; W: Wildtype. Significant differences are in italics (p < 0.05) or bold (p < 0.01) print.