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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Science. 2008 Dec 5;322(5907):1543–1546. doi: 10.1126/science.1163086

Figure 3. Rac depletion suppresses the cytokinesis defect in CYK-4GAP(E448K) embryos.

Figure 3

Time-lapse montage of the furrow region in embryos expressing a GFP::plasma membrane marker. Series begin at anaphase onset. A) CYK-4GAP(E448K) embryos exhibit partial furrow ingression followed by regression. B) Partial depletion of RhoARHO-1 enhances the CYK-4GAP(E448K) cytokinesis defect. C) RNAi of other Rho family members does not disrupt cytokinesis. D) Depletion of RacCED-10 or RacRAC-2 rescues cytokinesis success in CYK-4GAP(E448K) embryos. Scale bar, 20 μm.