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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Science. 2008 Dec 5;322(5907):1543–1546. doi: 10.1126/science.1163086

Figure 4. Negative regulation of Rac, WASP/WAVE, and the Arp2/3 complex by CYK-4 is essential for cytokinesis.

Figure 4

Cytokinesis in CYK-4GAP(E448K) embryos is rescued by co-depletion of A) the Rac effectors WASPWSP-1/WAVEWVE-1 or B) of the downstream target Arp2ARX-2. Scale bar, 20 μm. C) Model for signaling during cytokinesis.