Table 4. Estimation of time of divergence between M. ulcerans Agy99 and other M. ulcerans and M. marinum strains.
Strain | ds 1 | Est. divergence time2 (yr) | Est. divergence time3 (yr) |
NM31/04 | 0.000017±0.000004 | 1,466±345 | 1,090±256 |
NM20/02 | 0.00003±0.000006 | 2,586±517 | 1,923±385 |
Jp8756 | 0.006141±0.000081 | 529,397±6,983 | 393,654±5,192 |
M. marinum M | 0.017642±0.000138 | 1,520,862±11,897 | 1,130,897±8,846 |
mean±standard error
Based on the rate of synonymous substitution of 5.8×10−9 per site per year
Based on the rate of synonymous substitution of 7.8×10−9 per site per year