Table 1.
Clinical characteristics of patients in clinical study compared with pooled data from five major randomised controlled trials of patients receiving warfarin. Values for pooled data are percentages unless stated otherwise
| Clinical practice | Pooled data7 | Difference (95% CI) | |
|---|---|---|---|
| Mean age (years) | 77 | 69 | 7 (4 to 10)* |
| No (%) | |||
| <75 years | 87 (52) | 80 | −28 (−36 to −20) |
| >75 years | 80 (48) | 20 | 28 (20 to 36) |
| Men | 70 (42) | 75 | −33 (−41 to −25) |
| Hypertension | 72 (43) | 45 | −2 (−10 to 6) |
| Diabetes mellitus | 25 (15) | 13 | 2 (−4 to 8) |
| Current smokers | 22 (13) | 12 | 1 (−4 to 6) |
| Previous stroke or transient ischaemic attack (>6/12) | 23 (14) | 6 | 8 (3 to 13) |
| Congestive heart failure | 33 (20) | 20 | 0 (−6 to 6) |
| Ischaemic heart disease | 43 (26) | 36 | −10 (−17 to −3) |