Fig. 1.

Response of BALB/c mice to VV inoculation at sites of OVA sensitization. (A) Primary and satellite lesions in BALB/c mice inoculated with VV in unsensitized (-), saline-exposed (Sal.), and OVA-sensitized skin. (B) Largest diameter of primary lesion (n = 4–5 per group). (C) Number of satellite lesions (n = 5–12 per group). (D) Viral load in inoculated skin. VV genomes were detected in OVA-sensitized skin from seven of eight mice, but not in skin from five saline-exposed mice. (E) Viral load in internal organs (n = 3–7 per group). Values and error bars represent mean ± SD. *, P < 0.05; **, P < 0.01.