Table 1.
DKO's (Rbc−/c−;p107−/−;Cre+) die between e13.5 and e14.5
| Genotype* | p107+/− Rb+/cCre− | p107+/−Rb+/c−Cre+ | p107+/−Rbc/c−Cre− | p107+/− Rbc−/c−Cre+ | p107−/− Rb+/cCre− | p107−/− Rb+/c−Cre+ | p107−/− Rbc/c−Cre− | p107−/− Rbc−/c−Cre+ | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obs e13.5 | 30 | 35 | 19 | 13 | 25 | 26 | 18 | 25 | 191 |
| Exp e13.5 | 23.875 | 23.875 | 23.875 | 23.875 | 23.875 | 23.875 | 23.875 | 23.875 | 191 |
| Obs e14.5 | 12 | 11 | 13 | 12 | 14 | 12 | 10 | 9 (7)† | 93 |
| Exp e14.5 | 11.625 | 11.625 | 11.625 | 11.625 | 11.625 | 11.625 | 11.625 | 11.625 | 93 |
*Mice were generated from crosses of Rb+/c−;p107+/−;Mox2+/Cre males with Rbc/c;p107−/− females.
†Number in parentheses indicates dead embryos.