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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Mol Microbiol. 2008 Oct 30;71(1):79–91. doi: 10.1111/j.1365-2958.2008.06509.x

Fig. 1. Fitness of hma mutant in vitro and in vivo.

Fig. 1

(A) in vitro culture competition assay of wildtype CFT073 (filled symbols) and hma mutant (open symbols) cultured in Luria broth (solid line) or W salts minimal medium (dashed line). After inoculation (input CFU/ml plotted on y-axis), cultures were passaged into fresh medium every 8 (1:50 dilution) or 16 (1:500 dilution) hours. Arrows indicate culture passages. Means of triplicate cultures are plotted. *P=0.03.

(B) 72 hour CBA/J mouse co-infection with 108 CFU mixture of wildtype (WT) and hma mutant. Data points represent CFU/g of individual animals in the organs indicated; bars show median values (n=24).