Table 1. Expressed genes elevated in zfs1-deficient S. pombe that contain putative 3′-UTR AREs.
| S. pombe gene | Description | Statusa | Fold changeb | p value |
|---|---|---|---|---|
| SPCC1494.03 | Armadillo-repeat containing | Hypothetical | 4.30204 | <0.00E-45 |
| SPBC20F10.03 | Conserved eukaryotic | Hypothetical | 3.81255 | <0.00E-45 |
| SPAC343.06c | Phospholipid scramblase | Homology | 2.95178 | <0.00E-45 |
| SPAC8C9.16c | Mitochondrial oxidation resistance protein | Homology | 2.75289 | 3.20E-26 |
| SPAC4D7.10c | Histone acetyltransferase subunit | Homology | 2.38142 | 3.36E-24 |
| SPAC7D4.12c | Hypothetical protein | Hypothetical | 2.29411 | 3.99E-24 |
| SPAC30D11.07 | Nht1 DNA endonuclease III | Experimental | 2.18523 | 5.97E-18 |
| SPBC365.09c | CCHH zinc finger/conserved hypothetical | Homology | 1.90405 | 7.45E-11 |
| SPAC31A2.12 | Arrestin family | Homology | 1.84812 | 9.49E-27 |
| SPAC19G12.15c | Tpp1 (trehalose-6-phosphate phosphatase) | Experimental | 1.82499 | 8.57E-26 |
| SPBC17D11.01 | Nep1 (nedd8 protease) | Experimental | 1.75315 | <0.00E-45 |
| SPBC1289.13c | Galactosyltransferase | Homology | 1.67609 | 3.70E-31 |
a
Indicates the status of the characterization of these genes listed in the S. pombe gene database. “Experimental” indicates some level of experimental characterization, “Homology” indicates a description based on homology to known proteins of other species, and “Hypothetical” indicates a predicted protein that has not been assigned a specific description by homology.
b
Reflects increased transcript levels in the zfs1-deficient strain relative to wild type. This comparison is based on the means of four separate experiments in each case.