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. 2009 Sep 18;5(9):e1000586. doi: 10.1371/journal.ppat.1000586

Figure 5. Antigen-specific serum IgM and IgG is produced in vaccinated mice.

Figure 5

Serum from (A) ChuA-vaccinated, (B) Hma-vaccinated, (C) Iha-vaccinated, (D) IreA-vaccinated, (E) IutA-vaccinated, (F) IroN and IutA extracellular loop peptide antigens and corresponding CT control-treated mice was collected prior to vaccination (pre) and after vaccination before transurethral challenge with UPEC strain CFT073 (post). Samples were plated in duplicate in appropriately coated ELISA plates and probed for relative IgG and IgM. Open circles represent CT control mice and closed circles represent vaccinated mice. Each circle represents an individual animal and bars represent the median. Significance was determined using a two-tailed Mann-Whitney test.