Table 1. Antigens used to vaccinate mice.
Exp. number | Antigen | Relative protective efficacy in mouse model | Reference to antigen description or use as vaccine |
1 | FNE | − | [37] |
2 | SFS | − | [38] |
3 | FNEB | − | [18],[20] |
4 | EAG | + | [7],[20] |
5 | CNE | + | [10],[20] |
6 | SEQ0936, (putative pili) | + | This study |
7 | SEQ0944, (pullulanase) | + | This study |
8 | SEQ0256 | + | This study |
9 | IdeE | + | [16] |
10 | CNE+EAG | ++ | [20] |
11 | SclC | ++ | [12],[20] |
12 | EAG+SFS+FNE | ++ | [20] |
13 | EAG+CNE+SclC | ++ | [11] |
14 | IdeE2 | +++ | [19] |
15 | IdeE+IdeE2+EAG | +++ | This study |
16 | SEQ0402 | +++ | This study |
17 | SEQ0256+SEQ0402 | +++ | This study |
Ranking of efficacy on a range from − to +++ was based on weight loss and nasal colonization of mice challenged with S. equi after vaccination with indicated antigens.