Figure 5. Human β-globin expression in mice.
A. RBC parameters, reticulocytes and vector copies. Values represent means ± SEM. Hb = hemoglobin, MCV = mean corpuscular volume, MCHC = mean corpuscular hemoglobin concentration, vector copy = vector copies in leukocytes by qPCR. B. HPLC analysis of human β-globin protein in blood lysates as a percentage of total hemoglobin [hβ−mα / (hβ−mα + mβ−mα)]. Data is normalized to vector copy/cell in leukocytes. *P<0.05; **P<0.01.
