Table 3.
Pathologic Findings | Value |
---|---|
No. of glomeruli (mean) | 17.7 |
% of globally sclerotic glomeruli (mean) | 17.5 |
Predominant histologic pattern | |
membranoproliferative GNb | 21 (56.8) |
endocapillary proliferative GNb | 13 (35.1) |
mesangial proliferative GN | 1 (2.7) |
membranous GN | 2 (5.4) |
Crescentsc | 12 (32.4) |
focal | 10 |
diffuse | 2 |
Interstitial inflammation: None/focal/diffused | 4/28/5 (10.8/75.7/13.5) |
Tubular atrophy and interstitial fibrosis: None/mild/moderate/severee | 2/25/6/4 (5.4/67.6/16.2/10.8) |
Arteriosclerosis and arteriolar hyalinosis: None/mild/moderate/severe | 9/16/11/1 (24.3/43.2/29.7/2.7) |
Concurrent vascular amyloid | 1 (3) |
aGN, glomerulonephritis.
bWith or without membranous features.
cFocal, <50% of glomeruli; diffuse, ≥50% of glomeruli.
dFocal <50% of cortical surface area; diffuse ≥50%.
eMild, 0 to 25% of cortical surface area; moderate, 26 to 50%; severe, >50%.