Table 7.
Characteristic | Serum Creatinine at Biopsy (mg/dl) | 24-H Urine Protein at Biopsy(g/d) | M-Protein in Serum | % of Glomeruli with Crescents | Degree of Tubular Atrophy and Interstitial Fibrosis | Treatment | Duration of Follow-up (mo) |
---|---|---|---|---|---|---|---|
Patients with CR | |||||||
1 | 3.7 | 9.0 | No | 0 | Mild | PRED | 25 |
2 | 1.9 | 7.8 | No | 0 | Mild | RAS blockade alone | 67 |
3 | 2.2 | 7.5 | No | 0 | Moderate | PRED/CYT with CR then relapse treated with PRED/MMF with CR | 30 |
4 | 0.8 | 3.8 | No | 3 | None | RAS blockade alone | 114 |
Patients with PR | |||||||
1 | 1.7 | 3.5 | No | 0 | Mild | RAS blockade alone | 44 |
2 | 5.9 | 1.0 | No | 20 | Mild | PRED/CYT | 40 |
3 | 2.7 | 17 | No | 6 | Mild | Rituximab | 33 |
4 | 1.2 | 3.4 | No | 0 | Mild | RAS blockade alone | 4 |
5 | 1.3 | 5.0 | No | 4 | Mild | RAS blockade/MMF | 14 |
6 | 0.7 | 3.0 | No | 0 | Mild | Rituximab | 44 |
7 | 5.5 | 3.5 | IgG-λ | 0 | Mild | RAS blockade/PRED | 81 |
8 | 1.6 | 9.0 | IgG-κ | 0 | Mild | RAS blockade/PRED/chlorambucil | 93 |
Patient with persistent microhematuria | 0.7 | 0.36 | No | 0 | None | None | 8 |
aCYT, cyclophosphamide; MMF, mycophenolate mofetil; PRED, prednisone.