Table 5.
Logistic regression analysis testing association between per SD difference in baseline arterial stiffness measures and incident microalbuminuria in the Framingham Offspring Cohort (n = 1252)a
| Measures | Odds ratio (95% CI) | P Value |
|---|---|---|
| Carotid-femoral PWV (m/s) | ||
| Age and gender | 1.19 (1.00, 1.40) | 0.04 |
| Multivariableb | 1.14 (0.94, 1.42) | 0.17 |
| Forward pressure wave amplitude (mmHg) | ||
| Age and gender | 1.15 (0.96, 1.37) | 0.14 |
| Multivariableb | 1.24 (0.93, 1.66) | 0.15 |
| Central pulse pressure (mmHg) | ||
| Age and gender | 1.19 (0.99, 1.43) | 0.06 |
| Multivariableb | 1.33 (0.92, 1.93) | 0.13 |
| Augmentation pressure (mmHg) | ||
| Age and gender | 1.12 (0.94, 1.34) | 0.22 |
| Multivariableb | 1.0 (0.80, 1.27) | 0.96 |
| Augmentation index (%) | ||
| Age and gender | 1.04 (0.86, 1.26) | 0.70 |
| Multivariableb | 0.92 (0.73, 1.16) | 0.46 |
| Mean arterial pressure (mmHg) | ||
| Age and gender | 1.02 (0.99, 1.03) | 0.06 |
| Multivariableb | 1.02 (0.98, 1.06) | 0.37 |
aCI, confidence intervals; PWV, pulse wave velocity.
bMultivariable models include age, gender, baseline log urine albumin-to-creatinine ratio, body mass index, heart rate, mean arterial pressure (for models other than mean arterial pressure), diabetes, fasting blood glucose, total/HDL-cholesterol, lipid-lowering medication use, triglycerides, hypertension treatment, hormone replacement therapy in women, current smoking status, and prevalent cardiovascular disease.