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. 2009 Sep;20(9):2075–2084. doi: 10.1681/ASN.2008111205

Table 3.

Adverse events during the study perioda

Adverse Events Control (% of Patients) Bicarbonate (% of Patients) P
Hospitalization for CHF 0 0 N/A
Worsening hypertension requiring increase in therapy 48 61 0.17
Worsening edema requiring increase in loop diuretics 30 39 0.5
Bad taste requiring switch to powder form of sodium bicarbonate N/A 6.5 N/A

aCHF, congestive heart failure.