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. Author manuscript; available in PMC: 2009 Sep 2.
Published in final edited form as: Comp Med. 2007 Feb;57(1):82–89.

Figure 4.

Figure 4

Heme oxygenase 1 (HO1) induction during secondary bacterial infection. Mice were infected with 1000 TCID50 of influenza virus or mock infected with PBS and then challenged 7 d later with either PBS or 1 × 105 CFU of pneumococcus D39 (serotype 2). RNA was extracted from tissues and peripheral blood mononuclear cells (PBMCs) removed from groups of 5 to 7 mice 24 h after secondary challenge and assayed for heme oxygenase 1 by real-time PCR. The relative induction of heme oxygenase 1 is compared with that of mock-infected animals, whose average value was set at 1. *, P < 0.05 (analysis of variance with Dunn correction) versus other groups. Error bar, 1 standard deviation