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. Author manuscript; available in PMC: 2009 Sep 2.
Published in final edited form as: J Infect Dis. 2008 Apr 15;197(8):1189–1197. doi: 10.1086/529515

Figure 3.

Figure 3

T3SA- (a monoreassortant reovirus strain that is incapable of binding to sialic acid) was preincubated with glutathione S-transferase (GST) or GST-JAM-A (i.e., soluble GST fused to the extracellular domain of junctional adhesion molecule-A [JAM-A]) (A) or with monoclonal antibodies specific for the coxsackievirus and adenovirus receptor (RmcB) or for JAM-A (J10.4) (B). The virus-protein mixtures were adsorbed basolaterally to airway epithelia at an MOI of 100 pfu/cell. Epithelia were immunostained at 18 h after adsorption to detect reovirus proteins, and infected cells were quantified in 20 random fields of view from 3 individual airway cultures. Error bars denote SDs. *, P < .0001.