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. Author manuscript; available in PMC: 2009 Sep 2.
Published in final edited form as: Nature. 2008 May 7;453(7197):944–947. doi: 10.1038/nature06955

Figure 4.

Figure 4

The periodic transcription program is largely intact in cyclin mutant cells that arrest at the G1/S border. a, Genes maintaining periodic expression in cyclin mutant cells exhibit similar dynamics in b, wild-type cells. Each row in a and b represents the same gene (Supplementary Table 1). Transcript levels are depicted as shown in Fig. 1. c, Synchronously updating Boolean network model. Transcription factors are arranged based on the time of peak transcript levels in cyclin mutant cells. Arrows indicate transcription factor/promoter interaction. Activating interactions, outer rings; repressive interactions, inner rings. Coloring indicates activity in one of five successive states; SBF and YHP1 are active in two states (Supplementary Table 6).