Table 2.
Effect of different physiological conditions and xenobiotic treatments on induction of the tandemly-linked P450 members of the CYP63 family
| Variable | Fold expression | ||
|---|---|---|---|
| pc-1 | pc-2 | pc-3 | |
| Growth condition | |||
| High N vs Low N | 0.48 ± 0.18 * | 2.26 ± 0.23 * | 1.12 ± 0.07 * |
| 37 °C vs 22 °C (Low N) | 2.13 ± 0.04 | 0.84 ± 0.04 | 0.95 ± 0.06 |
| O2 vs Air (Low N) | 3.67 ± 0.10 | 17.69 ± 2.80 | 2.17 ± 0.48 |
| Carbon source | |||
| Sucrose vs Glucose | 0.77 ± 0.03 | 2.01 ± 0.02 | 0.80 ± 0.00 |
| Raffinose vs Glucose | 0.71 ± 0.01 | 2.43 ± 0.15 | 0.77 ± 0.19 |
| Starch vs Glucose | 0.37 ± 0.04 | 1.35 ± 0.19 | 2.00 ± 0.05 |
| CMC vs Glucose | 0.27 ± 0.07 | 1.63 ± 0.00 | 0.78 ± 0.02 |
| Xenobiotics | |||
| Aliphatics | 0.78 ± 0.20 – 5.11 ± 0.16 | 0.31 ± 0.03 – 31.48 ±0.32 | 0.07 ± 0.00 – 4.85 ± 0.15 |
| Aromatics | 1.36 ± 0.19 – 6.24 ± 0.24 | 0.64 ± 0.13 – 1.62 ± 0.06 | 1.50 ± 0.13 – 2.73 ± 0.00 |
| Poly aromatics | 1.38 ± 0.07 – 6.27 ± 0.48 | 1.02 ± 0.12 – 6.02 ± 1.39 | 0.93 ± 0.44 – 2.87 ± 0.09 |
| Alkyl-substituted aromatics | 0.34 ± 0.21 – 6.18 ± 1.14 | 0.76 ± 0.08 – 23.63 ± 7.5 | 0.01 ± 0.00 – 2.21 ± 0.11 |
| Alicyclics | 0.27 ± 0.32 | 0.24 ± 0.06 | 0.39 ± 0.02 |
| P450 inducers | 0.64 ± 0.41 – 4.97 ± 0.65 | 3.69 ± 0.31 – 3.81 ± 0.68 | 1.00 ± 0.22 – 1.19 ± 0.04 |
| Lignin derivatives | 0.89 ± 0.46 – 8.61 ± 1.35 | 0.72 ± 0.45 – 4.56 ± 2.31 | 1.69 ± 0.02 – 2.77 ± 0.09 |