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. 2009 Aug 20;9:15. doi: 10.1186/1472-6793-9-15

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Copyright © 2009 Arik et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of AaegPTEN knockdown on egg development: Newly eclosed Ae. aegypti were injected with 1.4 μg of dsRNA and allowed to recover for 48 h prior to blood feeding. A. Representative ovaries (24 h post bloodmeal) dissected from mosquitoes injected with dsRNA against AaegPTEN or DsRed (Control). B. Mosquitoes inoculated with AaegPTEN dsRNA produced significantly (* p = 0.0028) more mature follicles (106/ovary pair; n = 17) than the DsRed controls (74/ovary pair; n = 9). There was no significant difference in average follicle size (p = 0.31).