Table 2.
Human extracellular matrix molecules mRNA expression in periapical cysts, granulomas, and / or in healthy PDL tissue. mRNA expression was normalized by β-actin
Transcripts | Healthy PDL tissue | Granuloma | Cyst |
---|---|---|---|
ADAM metallopeptidase 13 | — | — | 1.22 ± 0.06 |
Collagen type XVIII α1 | 0.67 ± 0.24 | — | 1.14 ± 0.01 |
Catenin-α1 | 0.39 ± 0.11 | — | — |
Integrin-α3 | 0.46 ± 0.08 | — | 1.67 ± 0.01* |
Integrin-α5 | 0.79 ± 0.02 | — | 1.25 ± 0.01* |
Integrin-β1 | 0.75 ± 0.1 | — | 2.06 ± 0.01* |
Laminin-α5 | 0.74 ± 0.1 | — | 1.03 ± 0.01 |
Matrix metalloproteinase-24 | — | 1.05 ± 0.32 | 1.34 ± 0.59 |
Secreted phosphoprotein-1 | — | — | 1.38 ± 0.01 |
Transforming growth factor-β | 0.46 ± 0.04 | 1.01 ± 0.1* | — |
Tissue inhibitor of metalloproteinase-3 | 0.64 ± 0.21 | — | — |
L-selectin | 0.32 ± 0.12 | — | — |
p < 0.05 compared to healthy PDL tissue