Figure 6.

miRNA expression is negatively correlated with target mRNA expression. Predicted target mRNAs for each miRNA were identified using TargetScan 4.0 and compared with the lists of experimentally-determined, differentially-regulated mRNAs. A two-tailed Fisher's Exact Test was used to determine whether there were more predicted target mRNAs with differential expression than would be expected by chance (p < 0.05, above heavy black line at 4.3). The negative log of the p-value is plotted on the x-axis for both down-regulated mRNAs (grey) and up-regulated mRNAs (black).