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. 2008 Sep 20;26(27):4376–4384. doi: 10.1200/JCO.2007.14.4519

Table 2.

Enrichment Analysis of Genes Associated With Early Response

GeneOntology Term GeneOntology Number P
Hemocyte development GO:0007516 .00007
Vesicle targeting GO:0006903 < .001
Intercellular junction assembly GO:0007043 .001
Induction of apoptosis GO:0006917 .003
Cytoplasm organization and biogenesis GO:0007028 .004
Hemopoiesis GO:0030097 .005
Membrane fusion GO:0006944 .005
Hemopoietic or lymphoid organ development GO:0048534 .005
Nucleotide catabolism GO:0009166 .00004
Growth GO:0040007 < .001
Hormone-mediated signaling GO:0009755 < .001
Cellular morphogenesis GO:0000902 .002
Leukotriene biosynthesis GO:0019370 .002
Regulation of neuron differentiation GO:0045664 .003
Alkene biosynthesis GO:0043450 .004
Nucleosome assembly GO:0006334 .006
Cell growth GO:0016049 .007
Alkene metabolism GO:0043449 .007
Chromatin assembly GO:0031497 .009
Phospholipase C activation GO:0007202 .009

NOTE. The pathways upregulated in rapid early responders are hemocyte development through hematopoietic or lymphoid organ development; those upregulated in slow early responders are nucleotide catabolism through phospholipase C activation.