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. 2009 Aug 21;10:388. doi: 10.1186/1471-2164-10-388

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Copyright © 2009 Granata et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Intracellular reactive oxygen species (ROS) and serum 8-hydroxydeoxyguanosine (8-OHdG) levels in healthy subjects (HS), chronic kidney disease (CKD IV–V) and hemodialysis (HD) patients. The histograms represent the mean ± SD of 2',7'-Dichlorodihydrofluorescein (DCF) fluorescence (A) and serum 8-OHdG levels (B) in 12 HS, 10 CKD and 14 HD patients. DCF fluorescence in PBMC, reflecting the relative ROS levels, and the serum 8-OHdG levels were higher in HD and CKD compared to HS. In addition HD patients had higher 8-OHdG levels compared to CKD.