Table 3.
Mixed-effects regression models of cord blood DNA methylation, and lead biomarkers controlled for maternal age, maternal education, infant sex, and smoking status during pregnancy.
| Mean infant DNA methylation (β ± SE)
|
||
|---|---|---|
| Measure | Alu | LINE-1 |
| Cord blood lead | 0.176 ± 0.23 | 0.45 ± 0.49 |
| Maternal tibia lead | −0.027 ± 0.01** | −0.002 ± 0.02 |
| Maternal tibia leada | −0.027 ± 0.01# | −0.003 ± 0.02 |
| Maternal patella lead | −0.005 ± 0.01 | −0.020 ± 0.01 |
| Maternal patella leada | −0.007 ± 0.01 | −0.025 ± 0.01* |
a
Models also controlled for cord blood lead.
*
p < 0.10.
**
p < 0.05.
#
p < 0.01.