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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Cancer Res. 2009 Aug 25;69(17):7022–7029. doi: 10.1158/0008-5472.CAN-09-0925

Figure 3. A non-degradable mutant of claspin inhibits mitotic entry in HPV-16 E7-expressing cells.

Figure 3

The mitotic index was assessed in HPV-16 E7-expressing or empty vector control (LXSN) primary human keratinocytes 48 h after transient transfection with either a phospho-degron mutant of claspin (claspin S30/34A) or empty vector (control) using dsRED as a transfection marker. Mean values and standard error for LXSN cells were generated from a representative experiment with at least 100 cells counted in triplicate. Mean values and standard error for HPV-16 E7-expressing cells were generated from three independent experiments with at least 100 cells counted in triplicate. Asterisk indicates statistically significant differences in comparison to cells transiently transfected with empty vector (control).