Table 1.

Distribution and semi-quantitative description of intraneuronal and plaque-associated Aβ pathology based on 4G8 immunostaining

Brain region	Intraneuronal Aβ	Plaques
Olfactory bulb	+	+
Cortex	+/++	+
Hippocampus	+++	−
Thalamus	(+)	++
Superior colliculus	++	++
Midbrain	+	+
Pons	+	++
Medulla	++	+/++
Cerebellum
Purkinje cell layer	+++	−
White matter	−	++
Granule cell layer	−	−
Molecular layer	−	−