TABLE 4.

Case-control analysis after subdividing recurrent miscarriage (RM) patients by gender. Cochran-Armitage test for trend was performed for the variants in CGB5 and CGB8 genes showing significant association with RM in the full sample set (Table 3)

	Fertile women n=195	Female RM patients n=109			Male RM patients n=75
SNP	MAF %	MAF %	p-value	OR (95%CI)	MAF %	p-value	OR (95%CI)
c5EF-155	12.31	7.34	0.058	0.59 (0.32-1.03)	7.43	0.105	0.57 (0.26-1.13)
c5EF-147	12.05	6.88	0.039	0.53 (0.28-0.98)	7.43	0.115	0.57 (0.28-1.15)
c5EF-144	13.08	7.34	0.031	0.53 (0.29-0.95)	8.78	0.171	0.64 (0.34-1.22)
c5EF-142	13.08	7.34	0.031	0.53 (0.29-0.95)	8.78	0.171	0.64 (0.34-1.22)
c5EF1038	14.36	6.88	0.006	0.45 (0.25-0.81)	10	0.182	0.66 (0.36-1.22)

MAF - minor allele frequency; OR - odds ratio; CI - confidence interval