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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Microb Pathog. 2009 Jul 3;47(3):177–182. doi: 10.1016/j.micpath.2009.06.008

Figure 2. Role of IL-17A in protection from nasopharyngeal colonization induced by intranasal immunization with CWPS/1.

Figure 2

(A) Wild-type and (B) IL-17A-receptor knockout C57BL/6 mice (n=5–10 per group) were immunized, then challenged with type 6B pneumococcal strain 0603. IL-17A receptor-deficient mice were not protected (P>0.5 vs. CT by Mann-Whitney U) whereas wild type mice were significantly protected against NP colonization (P=0.03 by Mann-Whitney U). Depicted are the median and the interquartile range of density of colonization as determined by cfu of the nasal wash. Dashed line represents the lower limit of detection.