Table 1. Genes affected by Sp1 overexpression.
| Functional category | Symbol | Full name | Fold Change | UniGene | Ensembl | Affymetrix ID |
| Metabolism | ||||||
| Upp1 | uridine phosphorylase 1 | 5,0 | Mm.4610 | ENSMUSG00000020407 | 1448562_at | |
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 3,6 | Mm.306228 | ENSMUSG00000040710 | 1430391_a_at | |
| Galnt3 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 | 3,4 | Mm.38441 | ENSMUSG00000026994 | 1417588_at | |
| Slc39a8 | solute carrier family 39 (metal ion transporter), member 8 | 3,3 | Mm.30239 | ENSMUSG00000053897 | 1416832_at | |
| Tgm2 | transglutaminase 2 | 3,1 | Mm.330731 | ENSMUSG00000037820 | 1433428_x_at | |
| Mtap | methylthioadenosine phosphorylase | −2,1 | Mm.28500 | ENSMUSG00000062937 | 1424426_at | |
| Ubiquitin | ||||||
| Arih1 | ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 | 5,5 | Mm.305925 | 1442730_at | ||
| Fbxw2 | F-box and WD-40 domain protein 2 | 3,2 | 1454002_at | |||
| Pja2 | praja 2 | −2,0 | Mm.41711 | ENSMUSG00000024083 | 1427148_at | |
| Transcription | ||||||
| Jun | Jun | 3,8 | Mm.275071 | 1417409_at | ||
| Irf7 | interferon regulatory factor 7 | 3,5 | Mm.3233 | ENSMUSG00000025498 | 1417244_a_at | |
| Bcl9 | B-cell CLL/lymphoma 9 | −2,0 | Mm.87600 | ENSMUSG00000038256 | 1451574_at | |
| Sp1 | trans-acting transcription factor 1 | −2,3 | Mm.4618 | 1454852_at | ||
| Mecp2 | methyl CpG binding protein 2 | −2,5 | Mm.131408 | ENSMUSG00000031393 | 1438930_s_at | |
| Adhesion/Migration | ||||||
| Gsn | Gelsolin | 6,2 | Mm.21109 | ENSMUSG00000026879 | 1437171_x_at | |
| Arl6ip1 | ADP-ribosylation factor-like 6 interacting protein 1 | 5,3 | Mm.29924 | ENSMUSG00000030654 | 1423819_s_at | |
| Prickle1 | prickle like 1 | 3,4 | Mm.150314 | 1452249_at | ||
| Receptors/transmembrane | ||||||
| Neo1 | neogenin | 10,1 | Mm.42249 | ENSMUSG00000032340 | 1447693_s_at | |
| Tmem51 | transmembrane protein 51 | 6,5 | Mm.27587 | ENSMUSG00000040616 | 1424383_at | |
| Tmem71 | transmembrane protein 71 | 6 | Mm.132299 | ENSMUSG00000036944 | 1436212_at | |
| Tnfrsf22 | tumor necrosis factor receptor superfamily, member 22 | 3,9 | Mm.261384 | ENSMUSG00000010751 | ||
| Tmem173 | transmembrane protein 173 | 3,7 | Mm.45995 | ENSMUSG00000024349 | 1447621_s_at | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 3,4 | Mm.244187 | ENSMUSG00000028965 | 1428034_a_at | |
| Clec2d | C-type lectin domain family 2, member d | −2,3 | Mm.197536 | ENSMUSG00000030157 | 1419477_at | |
| Apoptosis | ||||||
| Bmf | Bcl2 modifying factor | 4,0 | Mm.210125 | ENSMUSG00000040093 | 1454880_s_at | |
| Cell cycle | ||||||
| Lats2 | large tumor suppressor 2 | 3,7 | Mm.347899 | ENSMUSG00000021959 | 1439441_x_at | |
| Exocytosis/Trafficking | ||||||
| Stxbp6 | syntaxin binding protein 6 (amisyn) | 7,4 | Mm.285400 | 1435396_at | ||
| Cd74 | class II antigen-associated, Ii | 3,9 | Mm.276499 | ENSMUSG00000024610 | 1425519_a_at | |
| Tcte1l | dynein light chain Tctex-type 3 | −2,0 | Mm.29150 | ENSMUSG00000031176 | 1449929_at | |
| Chemokine | ||||||
| Pf4 (Cxcl4) | chemokine (C-X-C motif) ligand 4 | 8,4 | Mm.332490 | ENSMUSG00000029373 | 1448995_at | |
| Inflammation | ||||||
| Gbp1 | guanylate nucleotide binding protein 1 | 7,8 | Mm.250 | ENSMUSG00000028269 | 1420549_at | |
| Gbp2 | guanylate nucleotide binding protein 2 | 5,1 | Mm.24038 | ENSMUSG00000028270 | 1418240_at | |
| Serpinf1 | serine (or cysteine) peptidase inhibitor, clade F, member 1 | 4,3 | Mm.2044 | ENSMUSG00000000753 | 1416168_at | |
| Signal transduction | ||||||
| Pik3r3 | phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) | 5,9 | Mm.253819 | ENSMUSG00000028698 | 1456482_at | |
| Eps8 | epidermal growth factor receptor pathway substrate 8 | 3,4 | Mm.235346 | ENSMUSG00000015766 | 1422824_s_at | |
| Ppp3cb | protein phosphatase 3, catalytic subunit, beta isoform | −2,1 | Mm.274432 | ENSMUSG00000021816 | 1433835_at | |
| Misclaneous | ||||||
| Hist2h2aa2 | histone cluster 2, H2aa2 | 11,0 | 1438815_at | |||
| E230032D23Rik | E230032D23Rik | 6,5 | Mm.387210 | 1444420_at | ||
| 4933411B09Rik | 4933411B09Rik | 4,7 | 1430863_at | |||
| 4,2 | 1443777_at | |||||
| RNAse k | ribonuclease, RNase K | 4,0 | Mm.29852 | ENSMUSG00000040904 | 1442441_at | |
| Ccdc19 | coiled-coil domain containing 19 | 3,6 | Mm.78373 | ENSMUSG00000026546 | 1429930_at | |
| 3110040M04Rik | 3110040M04Rik | 3,5 | Mm.359303 | 1429700_at | ||
| 3,5 | Mm.75540 | 1447844_at | ||||
| Calml4 | calmodulin-like 4 | 3,4 | Mm.28623 | ENSMUSG00000032246 | 1424713_at | |
| 4930513N10Rik | 4930513N10Rik | 3,2 | Mm.386996 | 1457415_a_at | ||
| Scoc | short coiled-coil protein | −2,0 | Mm.379079 | ENSMUSG00000063253 | 1416267_at | |
| Morc3 | microrchidia 3 | −2,1 | Mm.287329 | ENSMUSG00000039456 | 1452224_at | |
| Hba-a1 | hemoglobin alpha, adult chain 1 | −2,3 | Mm.196110 | ENSMUSG00000069917 | 1452757_s_at |
Genes identified by microarray analysis (Affymetrix GeneChip Microarray 430.2) as most up-regulated or down-regulated following ectopic Sp1 expression in Baf-Sp1 clone 1 (3 independent experiments). Differential gene expression following Sp1 deregulation relative to control was determined using GeneSpring GX 7.3 statistical analysis module ANOVA. The full list of deregulated genes following Sp1 overexpression with informations on each gene (ID, Gene Ontology, Kegg pathway, probeset quality, mean expression, mean deregulation) can be found at ftp://pbil.univ-lyon1.fr/pub/datasets/DeniaudE2009/.