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. 2009 Aug 31;206(9):2027–2035. doi: 10.1084/jem.20090560

Figure 2.

Figure 2.

Hypersensitivity of Ahr KO mice to LPS in vivo. 6-wk-old Ahr KO mice and littermate WT mice (n = 10 for each) were i.p. injected with 7.5 mg/kg of LPS. (A) Lethality was observed over 60 h after LPS challenge. Data are representative of two independent experiments. (B and C) Serum levels of IL-6 and TNF-α between WT and Ahr KO mice were measured by ELISA at indicated time points after LPS challenge. Data show means ± SEM of three independent experiments (*, P < 0.05; **, P < 0.01; ***, P < 0.001).