Figure 3.

Self-RNA–LL37 complexes are protected from enzymatic degradation. (A) Self-RNA alone, self-RNA–LL37 complexes, or self-RNA mixed with the control peptide GL37 were treated with RNase A and quantified over 60 min by a fluorometric assay. The percentage of protection was calculated as the ratio of remaining RNA over the initial RNA input. Data are representative of at least three experiments. (B) Agarose gel electrophoresis of self-RNA alone and self-RNA–LL37 complexes before and after RNase A treatment visualized by ethidium bromide staining.