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. Author manuscript; available in PMC: 2010 Aug 19.
Published in final edited form as: J Am Chem Soc. 2009 Aug 19;131(32):11581–11589. doi: 10.1021/ja904318w

Figure 1.

Figure 1

Four steps of protein splicing. During the four-step reaction, the intein (shown in red) is excised from the N-extein (shown in green) and C-extein (shown in blue), while the N-extein and C-exteins are ligated to form the mature protein.