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. 2009 Sep;134(3):231–241. doi: 10.1085/jgp.200910272

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© 2009 Beyl et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jgp.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 3. — Effects of pore mutations on steady-state activation and current kinetics. Voltage dependences of steady-state activation (A), time constants of activation (B; filled symbols), and deactivation (B; open symbols) of the indicated channel construct. Solid lines represent model simulations based on the identified model parameters given in Tables II and III.