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. 2009 Sep;134(3):231–241. doi: 10.1085/jgp.200910272

TABLE II.

Rate constants of A↔O and R↔D transitions (in ms−1)

Construct α β γ δ
Wild-typea 0.15 ± 0.11 0.24 ± 0.08 0.021 ± 0.021 1.39 ± 0.17
G770P 0.33 ± 0.31 0.31 ± 0.21 0.030 ± 0.073 0.56 ± 0.11
N771Pa 0.95 ± 0.63 0.11 ± 0.07 0.111 ± 0.057 1.41 ± 0.23
F778Pa 0.13 ± 0.12 0.28 ± 0.09 0.016 ± 0.026 0.70 ± 0.09
L779Pa 1.79 ± 0.81 0.11 ± 0.02 0.002 ± 0.002 0.36 ± 0.09
A780Pa 0.19 ± 0.03 0.0064 ± 0.0022 0.015 ± 0.005 0.14 ± 0.02
A780G 0.96 ± 0.62 0.27 ± 0.12 0.037 ± 0.022 2.10 ± 0.33
I781Ta 1.95 ± 0.91 0.045 ± 0.012 0.009 ± 0.003 1.02 ± 0.26
I781Pa 4.16 ± 1.86 0.034 ± 0.007 0.003 ± 0.001 0.74 ± 0.43
I781G 1.73 ± 0.81 0.036 ± 0.010 0.011 ± 0.003 0.78 ± 0.18
I781Aa 1.72 ± 0.79 0.132 ± 0.028 0.003 ± 0.001 1.55 ± 0.44
I781Va 0.55 ± 0.30 0.22 ± 0.03 0.0003 ± 0.0002 2.01 ± 0.77
I781Na 2.17 ± 0.99 0.10 ± 0.02 0.003 ± 0.002 0.74 ± 0.20
A782Pa 2.65 ± 1.23 0.111 ± 0.026 0.004 ± 0.002 0.94 ± 0.27
A782G 1.74 ± 0.97 0.32 ± 0.10 0.013 ± 0.009 1.96 ± 0.37
D784G 0.88 ± 0.53 0.34 ± 0.09 0.008 ± 0.006 1.62 ± 0.35
a

Rate constants estimated using data from Hohaus et al. (2005).