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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Bioconjug Chem. 2009 Jul;20(7):1412–1418. doi: 10.1021/bc900057z

Table 1.

Comparison of results between G4-(1B4M-Gd)30(CS) (A) and G4-(1B4M)60[Gd42] (CS) (B)

Agent G4:chelate r1 (mM-1s-1)a r2 (mM-1s-1)a Half life (min)b Rate of clearance (min-1)c
A 1:30 26.9 ± 1.2 56.1 ± 1.4 24.4 ± 4.74 0.029 ± 0.0047
B 1:41 13.9 ± 1.6 33.6 ± 3.1 72.7 ± 17.31 0.010 ± 0.0026
a

Molar relaxivity values obtained from phantom measurements.

b

Blood clearance half-life as measured from R1 map of the jugular vein in dynamic MR angiographic images.

c

Blood clearance rates. Reported numbers are the average values and errors are reported as standard deviations.