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. Author manuscript; available in PMC: 2009 Sep 3.
Published in final edited form as: Pharmacotherapy. 2008 Apr;28(4):437–443. doi: 10.1592/phco.28.4.437

Table 2.

Characteristics of the Study Populations by Diagnosis

Diagnosis
Characteristic Hypertension (n=457,395) Hypercholesterolemia (n=207,676) Type 2 Diabetes (n=105,225) Osteoporosis (n=42,007) Hypothyroidism (n=37,606) Gout (n=9715) Seizure Disorders (n=4984)

Mean ± SE
Age (yrs) 59.9 ± 0.02 57.7 ± 0.02 58.5 ± 0.04 64.8 ± 0.6 54.0 ± 0.07 58.7 ± 0.14 50.1 ± 0.24
Comorbidity scorea 0.67 ± 0.00 0.56 ± 0.00 0.81 ± 0.00 0.69 ± 0.00 0.55 ± 0.00 0.73 ± 0.00 1.14 ± 0.01

No. (%) of Patients
Sex
 Male 204,913 (44.8) 107,576 (51.8) 54,717 (52.0) 3025 (7.2) 7672 (20.4) 7529 (77.5) 2088 (41.9)
 Female 252,482 (55.2) 100,100 (48.2) 50,508 (48.0) 38,982 (92.8) 29,934 (79.6) 2186 (22.5) 2896 (58.1)
Type of health planb
 Comprehensive 161,003 (35.2) 66,422 (32.0) 35,987 (34.2) 17,999 (42.9) 11,461 (30.5) 3274 (33.7) 1585 (31.8)
 Exclusive provider organization 3659 (0.8) 2411 (1.2) 631 (0.6) 272 (0.7) 477 (1.3) 49 (0.5) 52 (1.0)
 Health maintenance organization 35,219 (7.7) 16,395 (7.9) 10,207 (9.7) 1253 (3.0) 2524 (6.7) 787 (8.1) 509 (10.2)
 Point of service 59,004 (12.9) 26,393 (12.7) 14,205 (13.5) 3726 (8.9) 5115 (13.6) 1263 (13.0) 661 (13.3)
 Preferred provider organization 172,438 (37.7) 81,395 (39.2) 37,986 (36.1) 16,824 (40.1) 15,217 (40.5) 3847 (39.6) 1810 (36.3)
 Point of service with cap 26,072 (5.7) 14,660 (7.1) 6209 (5.9) 1933 (4.6) 2812 (7.5) 495 (5.1) 367 (7.4)
Geographic area of residenceb
 Northeast 48,484 (10.6) 22,137 (10.7) 10,373 (9.9) 5387 (12.8) 3723 (9.9) 963 (9.9) 578 (11.6)
 North Central 140,878 (30.8) 68,512 (33.0) 32,836 (31.2) 14,774 (35.2) 11,771 (31.3) 3049 (31.4) 1490 (29.9)
 South 189,819 (41.5) 79,692 (38.4) 44,019 (41.8) 14,438 (34.4) 14,478 (38.5) 3875 (39.9) 1934 (38.8)
 West 78,214 (17.1) 37,335 (18.0) 17,997 (17.1) 7408 (17.6) 7634 (20.3) 1828 (18.8) 982 (19.7)
Previous drug therapyc 289,531 (63.3) 61,472 (29.6) 50,403 (47.9) 2940 (7.0) 3610 (9.6) 155 (1.6) 2148 (43.1)
Drugs added to the initial therapyb
 0 133,102 (29.1) 156,795 (75.5) 46,720 (44.4) 39,453 (93.9) 34,485 (91.7) 9433 (97.1) 2088 (41.9)
 1 146,824 (32.1) 40,705 (19.6) 37,565 (35.7) 2554 (6.1) 2933 (7.8) 282 (2.9) 1714 (34.4)
 ≥ 2 177,469 (38.8) 10,176 (4.9) 20,940 (19.9) 0 (0.0) 188 (0.5) 0 (0.0) 1182 (23.7)

SE = standard error.

a

Comorbidity scores equal the sum of medical care risk based on diagnoses; a higher score indicates higher risk.

b

Percentages may not equal 100% due to rounding.

c

History of drug therapy for the condition in the year before the newly started treatment.