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. 2009 Sep 11;4(9):e7012. doi: 10.1371/journal.pone.0007012

Table 2. CAN genes, their functions andcorresponding Accession number.

Gene Gene Name Gene Function References Accession Number
APC2 Adenomatosis polyposis coli 2 Wnt transduction pathway [25], [26] NM_005883.2
CD109 CD109 molecule Expressed in CD34+ acute myeloid leukemia and other blood cell lines [17] NM_133493.2
CHD5 Chromodomain helicase DNA binding protein 5 Intervenes in chromatin modification through histones acetylation and methylation [21] NM_015557.1
EVL Enah/Vasp-like Strenghtens cell-to-cell interaction [27] NM_016337.2
GPNMB Glycoprotein (transmembrane) nmb Expressed in low metastatic melanomas cell lines [23] NM_001005340.1
ICAM5 Intercellular adhesion molecule 5, telencephalin Highly expressed in the colony-stimulating factor of patients with acute encephalitis [22] NM_003259.2
LGR6 Leucin-rich repeat-containing G protein-coupled receptor 6 Receptor for glycoproteins Hormones [13] NM_021636.2
MMP2 Matric metallopeptidase 2 Active on angiogenic blood vessels, metastasis [16] NM_004530.2
PTPRD Protein tyrosin phosphatase, receptor-type, D TSG, involved in a wide range of common human cancers [51] NM_130391.2
RET Ret proto-oncogene Associated with multiple endocirine neoplasias type IIA and IIB [19] NM_020975.4
RNF182 Ring finger protein 182 Found to many transcriptional regulatory proteins [18] NM_152737.2
STARD8 START domain contain 8 TSG, inhibits cancer growth [27], [52] NM_014725.2
SYNE1 Spectrin repeat containing, nuclear envelope 1 Expressed in skeletal and cardiac muscles [14], [15] NM_182961.1